The UPBEAT trial allowed us to collect a huge amount of information on obesity during pregnancy. This includes data on over 300 women who developed diabetes during their pregnancies. Some of these women had completely normal births, while others suffered from complications. We want to understand what makes some women more likely to experience problems.
Over the last 12 months, we have completed our analysis of 1555 obese women who took part in the UPBEAT trial throughout pregnancy. We have been looking at factors such as ethnicity and family history of diabetes, as well as studying blood samples for “markers” that might give us clues of when a woman is at risk. By doing this, we’ll be able to see if any of these make it more likely for certain women with diabetes to have problems during pregnancy.
This work will be completed in 2018, with the hope that we’ll find results that can help us predict which women with diabetes are more at risk of complications during pregnancy. The earlier we know this, the better we can plan medical care that will help mother and baby have the best chance of a safe, healthy pregnancy.
This study takes place in a Tommy's centre and is funded by Tommy's, the National Institute for Health Research, Chief Scientist Office Scotland, Guy's and St Thomas' Charity, Diabetes UK and the Medical Research CouncilHide details