How does the immune system affect the chance of miscarriage?

David Lissauer, Mark Drayson, Mark Kilby, Paul Moss, Hoda Harb, Aurelio Tobias, Arri Coomarasamy

Tommy’s researchers want to find out more about the role of the immune system in women who have recurrent miscarriages, and see if immune testing can help us stop them.

During pregnancy, the immune system changes, helping to protect the baby growing in the womb. Recurrent miscarriages – 3 or more in a row – have been linked to problems with the way that the immune system adapts.

We want to find out more about the role of the immune system in miscarriage, and see if testing women’s immune systems could help us to stop them from happening. Scientists will look different substances in the blood and womb that suggest how well the immune system is working. By doing this, we will also be able to see if any of these substances are related to miscarriage.

We will also use Tommy’s Net to help us build models that could predict if a woman is likely to miscarry, based on multiple factors.

Thanks for your interest in our research

Tommy's funds research across the UK investigating the reasons for pregnancy complications and loss. Maternal and fetal research is underfunded and we need your support to continue. There are many small and large ways you can support us, find out more here.

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