Start: February 2018
End: February 2021
Why do we need this research?
Being obese increases the chances of complications during pregnancy. One medical condition linked to obesity is sleep apnoea, where a person stops breathing during sleep for short periods of time. These episodes can lead to a decrease in oxygen in the blood.
Scientists believe that sleep apnoea in obese pregnant women might contribute to pregnancy complications, such as gestational diabetes, high blood pressure, premature birth, and stillbirth. However, we don’t know enough about this to be certain. We also don’t know the extent of sleep apnoea in obese pregnant women. This is preventing us from helping these women to minimise risks during pregnancy.
What’s happening in this project?
Researchers funded by Tommy’s have set up the Sleep Easy Study to better understand the impact and extent of sleep apnoea during pregnancy. The team plan to recruit 80 pregnant women to the study, 40 who are obese and 40 who have a normal weight. The women are asked to wear equipment while they sleep which measures their breathing, heartbeat, and blood oxygen levels. This equipment can detect whether they are experiencing sleep apnoea or other sleep breathing disorders.
The women will also donate samples of their blood and their baby’s placenta and cord blood after birth. Our scientists plan to study the samples donated by the women, to understand what effect sleep apnoea has on mother and baby.
The team will also follow-up with the children when they are older, to investigate if their mother’s sleep apnoea causes any long-term effects for them.
What difference will this project make?
This project will help our scientists to better understand sleep apnoea during pregnancy, and what effect it has on mother and baby. Our researchers believe that sleep apnoea contributes towards pregnancy complications in obese women. If they find that this is indeed the case, then treating sleep apnoea could be a way to reduce the chances of problems during pregnancy for these women, and their children.
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Tommy's funds research across the UK investigating the reasons for pregnancy complications and loss. If you're interested in being kept updated about our research and news from Tommy's, click here.
New research has revealed the benefits of giving progesterone to women with early pregnancy bleeding and a history of miscarriage.
Tommy’s spent yesterday morning at the charming Foundling Museum in London, celebrating the work of Tommy’s National Centre for Maternity Improvement alongside the opening of the museum’s new exhibition, ‘Portraying Pregnancy’.
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A pilot trial led by Tommy’s National Centre for Miscarriage Research suggests diabetes drug could be repurposed to target the lining of the womb in women with recurrent miscarriage.