Why do we need this research?
We need to find ways to prevent pregnant women experiencing miscarriage. Clinical trials can be used to test new treatments and interventions. However, they can be expensive to run, and may need thousands of women to take part, which can be difficult to achieve.
New methods to test treatments and interventions are needed, so that we can find the best ways to prevent miscarriages.
What’s happening in this project?
Building on the success of the Tommy’s Net project, our researchers are developing a new way to test interventions to prevent miscarriage.
In normal clinical trials, a group of people are selected to test a treatment, where some people get the treatment and the rest get standard treatment. Normally, each new treatment needs its own clinical trial.
Our researchers will use a system called ‘cohort multiple randomised clinical trials’, or cmRCT. Instead of settings up separate trials for different treatment, the team hope to recruit one large group of women, called a cohort, and test multiple treatments on different people within the same group. This will mean that the researchers don’t have to recruit new people for each trial, saving time and money.
The team’s first step to making this happen is to get permission from NHS Digital to access health care information from the women in the cohort. This will mean that information about the women’s health and pregnancy will be automatically sent to the researchers, and can be linked with any new interventions they may be receiving.
What difference will this project make?
Our researchers hope that this new way of conducting clinical trials will help to make miscarriage research much easier and faster. This could mean that treatments and tests could reach women across the UK sooner, and help to reduce the number of miscarriages in the future.
Thanks for your interest in our research
Tommy's funds research across the UK investigating the reasons for miscarriage, stillbirth and premature birth. We can keep you updated on ways you can support our work. If you would like to join our fight against baby loss and premature birth, click here.
More miscarriage research projects
A recently published article, co-authored by Professor Catherine Williamson from Tommy’s Research Centre at King’s College London, suggests that certain pregnancy complications can indicate future health issues for women.
Tommy’s has received a grant from the UK Government’s Department for Health and Social Care to support the costs of its PregnancyHub information and support services throughout the summer, due to rising demand in the wake of coronavirus.
Although recruitment to some clinical trials had to be paused when coronavirus hit the UK, scientists at Tommy’s Research Centres across the UK are still hard at work, supporting women and families in our specialist clinics and sharing their latest studies with academic journals.
The day before Mother’s Day, and two days before the UK officially went into coronavirus lockdown, Zara Dawson found out she was having a miscarriage. Her third consecutive miscarriage in less than a year, and fourth consecutive loss, after losing her second son Jesse in 2018 to termination for medical reasons.