Tommy's news, 15/11/2017
Today, research was released that links vitamin D with better live birth rates in women undergoing assisted reproduction treatment (ART).
Researchers from Tommy’s National Centre for Miscarriage Research at the University of Birmingham investigated the connection between vitamin D and the outcomes of assisted reproduction treatment, such as IVF and frozen embryo transfer.
The team analysed data from 11 studies that included 2,700 women who were undergoing ART. They found that live births were a third more likely to occur in women who had the right amount of vitamin D compared to women who did not.
The researchers also found that women who had sufficient vitamin D were 34% more likely to have a positive pregnancy test and 46% more likely to achieve a clinical pregnancy, compared to women who had low levels of vitamin D.
Lead researcher Dr Justin Chu has cautioned that the findings do not mean that vitamin D supplementation necessarily improves women’s chances of having a baby following ART, as the research can only show an association.
However, these promising findings do highlight the need for more investigation in this area. Researchers are calling for a clinical trial to further investigate the potential role of vitamin D in pregnancy.
Dr Chu said,
‘Although an association has been identified, the beneficial effect of correction of vitamin D deficiency or insufficiency needs to be tested by performing a clinical trial.’
‘In the meantime, women who want to achieve a successful pregnancy should not rush off to their local pharmacy to buy vitamin D supplements until we know more about its effects.’
‘It is possible to overdose on vitamin D and this can lead to too much calcium building up in the body, which can weaken bones and damage the heart and kidneys.’
Our main source of vitamin D is sunlight. Other studies have shown that there are higher conception rates in summer and autumn when women might be expected to have more vitamin D due to exposure to summer sunshine. Foods such as oily fish, red meat, liver and egg yolks also provide vitamin D, as well as vitamin D supplements.
The team say that possible roles played by vitamin D in pregnancy may be that it affects the success of embryo implantation in the womb in some way, or that it indicates the general wellbeing of the women.
Dr Chu added,
‘Testing for vitamin D concentrations is relatively cheap and widely available and its treatment is not costly.’
‘It could be that correcting vitamin D deficiency could benefit women undergoing assisted reproduction treatment, but further research is needed to test this.’
Find all the information you will need for getting pregnancy ready.
Read more about the study on the Human Reproduction website.
New research has revealed the benefits of giving progesterone to women with early pregnancy bleeding and a history of miscarriage.
Tommy’s spent yesterday morning at the charming Foundling Museum in London, celebrating the work of Tommy’s National Centre for Maternity Improvement alongside the opening of the museum’s new exhibition, ‘Portraying Pregnancy’.
Miscarriage and ectopic pregnancy may trigger long-term post-traumatic stress, anxiety and depression
The largest ever study into the psychological impact of miscarriage and ectopic pregnancy has shown that early-stage pregnancy loss can have a serious impact on mental health. The research was led by Professor Tom Bourne at the Tommy’s National Centre for Miscarriage Research at Imperial College London.
A pilot trial led by Tommy’s National Centre for Miscarriage Research suggests diabetes drug could be repurposed to target the lining of the womb in women with recurrent miscarriage.