Tommy's news, 19/06/2019
New research funded by Tommy's and the UK Medical Research Council, suggests that babies born to mothers who were obese during pregnancy are three times more likely to develop type 2 diabetes in later life.
The study also found that being overweight, but not obese, during pregnancy increases risk of diabetes in the child by almost half.
The findings add to the list of health problems linked to offspring of obese pregnant women, which also include heart disease, behavioural problems and early death.
Researchers say public health interventions are urgently needed to help women who may be planning pregnancies to maintain a healthy weight.
Tommy's Chief Executive, Jane Brewin comments:
‘This research adds to the growing body of evidence that maternal health before, as well as during, pregnancy affects the health of children into the future. The cycle of ill-health caused by obesity is particularly damaging to future generations. We need wider awareness of the importance of health before conception as well as supportive and accessible programmes that help women who have a high BMI to lose weight before pregnancy and manage their weight during pregnancy. This would return dividends with a healthier future generation as well reducing the many pregnancy complications associated with obesity.’
The team studied birth records from more than 100,000 people born between 1950 and 2011 in the Aberdeen area and linked them with the national register for diagnosed diabetes in Scotland.
Figures revealed around one quarter of women were overweight during pregnancy over the 60-year period. One in ten were obese, with a body mass index (BMI) greater than 40.
The proportion of obese mothers increased five-fold from around one in 30 during the 1950's to almost one in six between 2000 and 2011.
Children from mums who were overweight or obese during pregnancy were more likely to develop either type of diabetes in their lifetime – type 1 or type 2 – the study revealed. Risks were higher for type 2 diabetes.
The researchers did not look at BMI of the offspring, or other lifestyle factors such as diet and exercise that are known to increase risk of type 2 diabetes. They say shared lifestyle between mother and child could contribute to the development of the condition.
Further studies are needed to better understand how a high BMI during pregnancy leads to diabetes in offspring. One theory is that it may cause an adverse environment in the womb, where high levels of sugar and insulin trigger metabolic processes in the fetus that lead to diabetes.
Around half of all women of childbearing age are overweight or obese in the UK, recent figures suggest. The researchers say there is an urgent need to establish effective interventions to prevent obesity during pregnancy.
The study, published in the journal Diabetologia, was funded by Tommy’s, the baby charity, and the UK Medical Research Council.
Professor Rebecca Reynolds, of the Tommy’s Centre for Maternal and Fetal Health at the University of Edinburgh, said:'
'We found an increased risk of developing diabetes in children born to obese mothers, which was not linked to sociodemographic factors. Our findings underline the urgent need to find ways of helping women plan for pregnancy by optimising their health – including reaching and maintaining a healthy weight.'
How Tommy's is working to change this
In addition to our core work on miscarriage, stillbirth, preterm birth and pre-eclampsia, Tommy’s also funds research into the effects of lifestyle and well-being on pregnancy and on the later life of the child.
We fund projects that further the body of evidence available to the bodies, such as NICE, who make recommendations on the information that should be given to pregnant women.
We also research the best ways to deliver information and interventions to hard-to-reach groups, such as young women, who are more at risk of pregnancy complications due to lifestyle issues.
Planning a pregnancy
If you've decided you're ready to start a family, find out how to get pregnant and some of the lifestyle changes that might help you.
A recently published article, co-authored by Professor Catherine Williamson from Tommy’s Research Centre at King’s College London, suggests that certain pregnancy complications can indicate future health issues for women.
Tommy’s has received a grant from the UK Government’s Department for Health and Social Care to support the costs of its PregnancyHub information and support services throughout the summer, due to rising demand in the wake of coronavirus.
Although recruitment to some clinical trials had to be paused when coronavirus hit the UK, scientists at Tommy’s Research Centres across the UK are still hard at work, supporting women and families in our specialist clinics and sharing their latest studies with academic journals.
The day before Mother’s Day, and two days before the UK officially went into coronavirus lockdown, Zara Dawson found out she was having a miscarriage. Her third consecutive miscarriage in less than a year, and fourth consecutive loss, after losing her second son Jesse in 2018 to termination for medical reasons.