January 15 2020
Post-traumatic stress disorder (PTSD) after early pregnancy loss
The research, published in the American Journal of Obstetrics and Gynaecology, studied 737 women who had experienced an early pregnancy loss, with the majority having an early miscarriage or an ectopic pregnancy.
The study revealed that 1 month following pregnancy loss, nearly a third of women suffered post-traumatic stress while 1 in 4 experienced moderate to severe anxiety.
The team behind the research, funded by the Imperial Health Charity and the Imperial NIHR Biomedical Research Centre, call for immediate improvements in the care women receive following an early-stage pregnancy loss.
“Pregnancy loss affects up to 1 in 4 women, and for many women it will be the most traumatic event in their life. This research suggests the loss of a longed-for child can leave a lasting legacy and result in a woman still suffering post-traumatic stress nearly a year after her pregnancy loss.
“The treatment women receive following early pregnancy loss must change to reflect its psychological impact, and recent efforts to encourage people to talk more openly about this very common issue are a step in the right direction. Whilst general support and counselling will help many women, those with significant post-traumatic stress symptoms require specific treatment if they are going to recover fully. This is not widely available, and we need to consider screening women following an early pregnancy loss so we can identify.”
Professor Tom Bourne, lead author of the research from Tommy’s National Centre for Miscarriage Research at Imperial College London
More about the study
The research follows an earlier pilot study in 2016, which investigated the psychological impact of early-stage pregnancy loss in 128 women 1 and 3 months after miscarriage or ectopic pregnancy. Estimates suggest there are 250,000 miscarriages every year in the UK, and around 11,000 emergency admissions for ectopic pregnancies. Ectopic pregnancies always result in pregnancy loss, as an embryo grows in an area outside of the womb and is unable to develop.
The women in the study attended the Early Pregnancy Assessment Units at 3 London hospitals - Queen Charlottes and Chelsea, St Mary’s, and Chelsea and Westminster. All were asked to complete questionnaires about their emotions and behaviour 1 month after pregnancy loss, then again 3 and 9 months later
Their responses were compared to 171 women who had healthy pregnancies. The results revealed that women who had suffered early pregnancy loss experienced increased psychological symptoms, compared to those who had healthy pregnancies.
The women in the study who met the criteria for post-traumatic stress reported regularly re-experiencing the feelings associated with the pregnancy loss and suffering intrusive or unwanted thoughts about their miscarriage. Some women also reported having nightmares or flashbacks, while others avoided anything that might remind them of their loss.
The authors note that the study used a questionnaire to screen for post-traumatic stress, but formal diagnosis of post-traumatic stress disorder would require a clinical interview. The team also explain that women who were already experiencing symptoms of post-traumatic stress and depression may have been more likely to respond to the questionnaire, which could mean the number of women suffering psychological symptoms may appear higher.
The long-lasting effects of PTSD
“The effects of post-traumatic stress can have a toxic effect on all elements of a person’s life – affecting work, home and relationships. We have made significant progress in recent years in breaking the silence around mental health issues in pregnancy and postnatally, but early pregnancy losses are still shrouded in secrecy, with very little acknowledgement of how distressing and profound an event they are.
“Many women don’t tell colleagues, friends or family they are pregnant before the 12-week scan, leaving them feeling unable to discuss their emotions if they suffer a pregnancy loss. We also know partners can suffer psychological distress following miscarriage or ectopic pregnancy and are investigating this in ongoing research.”
Dr Jessica Farren, author of the research from Imperial College and Obstetrician and Gynaecologist
The team’s research will also now focus on identifying which women are at risk of developing psychological symptoms after pregnancy loss, and also the best type of treatments and how to deliver these.
“For too long women have not received the care they need following a miscarriage and this research shows the scale of the problem. Miscarriage services need to be changed to ensure they are available to everyone and women are followed up to assess their mental wellbeing with support being offered to those who need it and advice is routinely given to prepare for a subsequent pregnancy.”
Jane Brewin, Chief Executive of Tommy’s
Our work is funded with donations. Without your gifts we will not be able to fund research into the causes and prevention of miscarriage, stillbirth and premature birth.
Premature birth is the biggest killer of newborn babies in the UK and much of Tommy's research is devoted to predicting and preventing this. One discovery has made a huge difference to our ability to treat women in time.
In more than half of stillbirths parents are not given a reason for their babies' death. Doctors simply do not know why it happens. This animation looks at how Tommy's researchers are finding out the causes of stillbirth and how this leads to treatments and saved lives.
Too many miscarriages are unexplained. Our research is entirely dedicated to finding out why miscarriages happen and how to prevent it in the future.
A pilot trial led by Tommy’s National Centre for Miscarriage Research suggests diabetes drug could be repurposed to target the lining of the womb in women with recurrent miscarriage.
More than a third of maternity doctors admitted they suffer from burnout and exhaustion. This means that they may avoid difficult cases, over-prescribe medications and care less about their patients, increasing the risk of mistakes.
Abdominal stitch is more effective than vaginal stitch for women who experience recurrent preterm births
A clinical trial has shown that an abdominal stitch can save babies’ lives by reducing preterm birth for high-risk women who have had a previous failed vaginal stitch. The trial was led and co-authored by Professor Andrew Shennan, Clinical Director of Tommy’s Preterm Surveillance Clinic.
Chloe, founder of ‘Embaby Art’, sits down to have a chat with Tommy’s about her passion for creating personalised paintings for families going through IVF.